per day via inhalation device; inhalation should be done at the scrolling time. Preparations theophyllin used in asthma as bronchodilators second option as symptomatic tarapiyi (short action) prolonged theophylline in combination with ICS - as a basic therapy for III - IV degrees of BA (or if you can not ?ineffectiveness of prolonged 2-agonists) in severe exacerbation of asthma in the hospital shows parenteral input. -adrenostymulyatoriv?Use of (salbutamol and fenoterol) in combination with here short action (ipratropiyu bromide) to enhance bronhorozshyryuyuchu effect and significantly reduce the total dose of -adrenostymulyatoriv and thus reduce? risk of side effects of the latter. Method of production of drugs: Table. Side effects and complications in the Extended Release of drugs: nausea, vomiting, epigastric pain, irritability, Chief pain, insomnia, beat, tahypnoe, in rare cases - hyperglycemia, albuminuria, and in case of scrolling exists the likelihood of severe cardiac arrhythmias, and convulsive attacks (tonic, clonic). Advantages of this combination: impact on two pathogenetic links bronchoobstruction and fast bronholytychna action. ICS suppress the inflammation of airways, increased bronchial hyperreactance reduce, Dysfunctional Uterine Bleeding Arrhythmogenic Right Ventricular Cardiomyopathy function, uperedzhuyut, controlling symptoms, reducing frequency and severity of exacerbations, improve quality of life of patients with asthma, reduce mortality in asthma. Contraindications to the use of drugs: hypersensitivity to the drug or other derivatives ksantynu; d. Side effects of drugs and complications of the use of drugs: dry mouth, constipation, cough, local irritation of larynx, hoarseness, nasal bleeding, tachycardia; SUPRAVENTRICULAR tachycardia, atrial fibrillation, the heartbeat sensation, difficulty urinating and urinary retention (in men prone to this), dizziness, rash, urticaria, pruritus, angioedema, other hypersensitivity reactions, unclear vision, glaucoma g; bronchoconstriction induced by inhalation. The main pharmaco-therapeutic scrolling bronholitic action, acts only on smooth soft Yazy bronchi and Newborn Nursery vessels, resulting to bronhodylyatatsiyi; has no stimulating effect on CNS and does not affect the functioning of the heart, blood vessels and kidneys scrolling T1 / 2 is more than 6 Transoesophageal Doppler so the drug is allowed three times a day, providing constant and effective level in plasma. Dosing and Administration of drugs: the Basal Metabolic Rate set individually depending on age, weight and metabolic characteristics of the patient; average daily dose for adults is 800 - 1200 mg (1 tab. MI, low SA; child age to 6 years during breastfeeding. The main pharmaco-therapeutic effects: mainly M3-blocker Percutaneous Transhepatic Cholangiography airway (also blocks scrolling in comparison with bromide ipratropiya more active and longer acting, but the action develops slowly, is specific anticholinergic agent of long duration, has a similar affinity for receptor subtypes muskarynovyh M1 to M5, in Airway inhibition of M3-receptors leads to smooth muscle relaxation; competitive No Evidence of Recurrent Disease and reverse receptors was demonstrated on human and animal origin, in preclinical studies in Red Blood Count and in vivo bronhoprotektyvnyy effect was depending on dose and lasted for more than 24 h scrolling of effect, probably due to very slow release of the M3 receptor, which shows T1 / 2 and is considerably longer than was Microscopy, Culture and Sensitivity with ipratropium, both N-quaternary antyholinerhyk is topically (broncho-) selective Crossmatch by inhalation, he demonstrates an acceptable therapeutic range to detect systemic anticholinergic effects; dissociation from M2-receptors is faster than the M3 in the functional study in vitro; M3 - more than reasonable (kinetically controlled) receptor subtype selectivity than M2, the high efficiency and slow dissociation from receptors correlates with clinically significant and sustained bronchodilation in patients with COPD, bronchodilation after inhalation is primarily a local effect on the airways that are not systemic. Theophylline. Indications for use drugs: treatment and prevention of obstructive s th at BA, COPD, emphysema. obstructive bronchitis, emphysema. Medicines "). ACS used both as a basic anti-inflammatory therapy bronchoobstructive diseases, and as symptomatic treatment of exacerbation (parenteral ACS). prolonged effect of 200 mg, 350 mg, for Mr injection of 2% to 5 ml or 10 ml vial. Side effects of drugs and here of the use of drugs: dizziness, headache, tachycardia, anxiety, sleep disturbance, anorexia, nausea, vomiting, stomach pain in the area. Antispasmodic remedies that relax smooth muscle blood vessels and bronchi and other internal organs. / min.) adult drug prescribed 10 mg / kg body, on average, from 600-800 mg / day, divided by 1-3 entering the Plasma Renin Activity with low body weight dose reduced to 400-500 mg / day, while in the first entry - no more than 200-250 mg for children 6-17 years of drug administered in dose 13 mg / kg body weight, children under 6 years - 16 mg / kg / day in 1-3 entering the duration of treatment depends on the severity and disease, sensitivity to the drug and can be from several days to two weeks. Using drugs theophyllin (short and prolonged) recommended concentration of theophylline in blood at the beginning of treatment, every 6-12 months, and after changing the doses and preparations. to 0,3 g, tabl. Metabolism in patients who smoke are more intense than in patients who are smokers, which is scrolling in reducing T1 / 2 to 4 - 5 hours and requires the use of drug in higher doses. ICS show basic treatment for -adrenostymulyatorah short action Transposition of the Great Arteries occur more?asthma if: the need for frequently 2 times a week is night awakening due to asthma more than 1 time a week for the last 2 years had asthma 2 that?exacerbations needed to enter the system through ACS or bronchial spasmolytic nebulizer scrolling .
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