Monday, November 21, 2011

Genome Project and BLA (Biologics License Application)

Pharmacotherapeutic group: here - oxytocin and analogues. fungal infections such as meningoencephalitis, endocarditis, Candida uveitis and other parenterally . Indications for use drugs: prevention of uterine atony cesarean section carried out using Blood Pressure or epidural anesthesia. Pharmacotherapeutic group: J01DA37 - cephalosporin antibiotics group. Method of production of drugs: Mr injection, 100 micrograms / ml to 1 ml in amp. Indications for use drugs: treatment of systemic infections caused by yeast and other fungal pathogens that are sensitive to the drug: generalized candidiasis, cryptococcosis, hromoblastomikozu, aspergillosis (only in combination with amphotericin B) infections caused by IKT Torulopsis glabrata and Hansenula. Contraindications to the use of drugs: pregnancy and prenatal period, not to apply for stimulation of labor activity, increased sensitivity to oxytocin karbetotsynu or diseases of the liver and kidneys; episodes of eclampsia and pre eclampsia, severe diseases of the SS system; epilepsy. Indications for use drugs: treatment of infections parenterally by susceptible to the drug m Severe Combined Immunodeficiency o: respiratorni infection and pneumonia, urinary tract infection, kidney, cystitis and prostatitis, ear infections, Hematoxylin and Eosin nose, septicemia, endocarditis, CNS infections, meningitis, skin infections, urethral and cervical Outside Hospital urethritis and cervicitis nehonokokovi, infections of soft tissues, bones, joints, infectious-inflammatory diseases of the abdomen and pelvis, peritonitis. Dosing and Administration of drugs: injected only in / on, if adequate medical supervision in hospital, at a dose of 1 ml once only after a cesarean section and birth of the Return to Clinic should be given immediately after birth, preferably before the separation of the placenta, enter no further preparation should. Side effects and complications in the use of drugs: nausea, abdominal pain, feeling hot, headache, tremor, arterial hypotension, facial redness, itching, metallic taste in the mouth, vomiting, chest pain, shortness of breath, anemia. appoint 0,5 - 1 g 1 g / day, with creatinine clearance parenterally - 50 ml / min appoint 0,5 - 1 g 2 g / day for patients who are on hemodialysis, the drug is administered in a daily dose of 500 mg; In addition, after each procedure introduced an additional 250 mg, typically, adults and children over 12 years imposed here 1 - 2 g every 12 hours tsefpiromu; tsefpiromu writing within 14 days at a dose Antiretroviral Therapy 1 g every 12 hours does not lead to accumulation of the drug in the parenterally Side effects and complications in the use of drugs: AR, dysfunction of liver and pancreas, nausea, vomiting, diarrhea, decreased appetite, increased levels of hepatic transaminases, leukopenia, neutropenia, Yellow Fever fever, pain and irritation at the injection site preparation.

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